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MetabolicExperimentalResearch UseOral

SLU-PP-332

SLU-PP-332 is a novel compound developed at Washington University that activates ERR (estrogen-related receptor) gamma, alpha, and beta — the same transcription factors activated by aerobic exercise. It essentially tricks the body into experiencing some molecular benefits of exercise, including increased fat oxidation, improved mitochondrial function, and enhanced muscle endurance. In animal studies, mice treated with SLU-PP-332 could run significantly longer and had improved metabolic profiles. It is an oral compound and represents a new class of "exercise mimetics."

Frequency

1-3 times daily

Cycle Length

Research is still emerging. Typical: 4-8 weeks.

Route

Oral

Research Level

Experimental

Goals

Fat LossEnergyMitochondrial HealthMuscle Growth

Dosing Protocol

250 mcg to 200 mg orally, 1-3 times daily. Available in 250 mcg (60 ct), 1 mg (60 ct), and 200 mg (60 ct) tablets. For weight loss, use lower dose; for lean muscle, use higher dosage.

Timing

Morning.

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Potential Side Effects

  • Limited human safety data
  • Potential GI upset
  • Novel compound — use with caution

Important Warnings

  • Preclinical compound — no human clinical trials
  • Long-term safety completely unknown

Research References

  1. Kim W, et al. J Med Chem. 2023;66(11):7487-7500. doi:10.1021/acs.jmedchem.3c00281

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Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. SLU-PP-332 may be regulated differently in various jurisdictions. Always consult with a qualified healthcare provider before beginning any peptide protocol. PepStack Pro does not sell peptides or provide medical advice. Content reviewed by Dr. Seth Miller, MD.