5-Amino-1MQ
5-Amino-1MQ is a small molecule that inhibits the enzyme NNMT (nicotinamide N-methyltransferase), which plays a key role in energy metabolism and fat storage. By blocking NNMT, this compound increases NAD+ levels in fat cells, reactivating cellular metabolism and promoting fat loss while preserving and potentially increasing lean muscle mass. Taken orally, making it one of the few non-injectable peptide-adjacent compounds.
Frequency
1 to 3 times daily
Cycle Length
30 days on, 15-30 days off
Route
Oral
Research Level
Emerging
Goals
Dosing Protocol
15-150 mg daily, taken orally in tablet form. Typical starting dose is 15 mg (1 tablet).
Timing
Morning with breakfast.
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Potential Side Effects
- Mild GI discomfort
- Headache
- Generally well tolerated
Important Warnings
- Not FDA-approved — sold as a research compound
- Limited long-term human safety data
Works Well With
Research References
- Neelakantan H, et al. Biochem Pharmacol. 2018;147:141-152. doi:10.1016/j.bcp.2017.11.007
- Kannt A, et al. Biochem Pharmacol. 2018;154:1-9. doi:10.1016/j.bcp.2018.04.014
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Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. 5-Amino-1MQ may be regulated differently in various jurisdictions. Always consult with a qualified healthcare provider before beginning any peptide protocol. PepStack Pro does not sell peptides or provide medical advice. Content reviewed by Dr. Seth Miller, MD.