GHRP-2
Growth Hormone Releasing Peptide-2 is one of the most potent synthetic GH secretagogues available. It stimulates the pituitary gland via the ghrelin receptor, producing robust GH pulses. GHRP-2 is known for significantly increasing appetite (via ghrelin mimicry), making it ideal for individuals looking to gain lean mass. It also elevates IGF-1, improves sleep quality, and supports recovery. Compared to GHRP-6, it produces slightly less hunger but more consistent GH output.
Frequency
5 days per week, up to 8 weeks
Cycle Length
Up to 8 weeks on, 4 weeks off
Route
Subcutaneous
Research Level
Established
Goals
Dosing Protocol
200 mcg to 1 mg per day, split across doses. With standard reconstitution (10 mg in 3 mL), 0.033 mg per unit — 6 units = 200 mcg, 30 units = 1 mg on a U-100 insulin syringe. Inject on empty stomach 30 minutes before meals. Gradual dose increase may increase appetite.
Reconstitution
Add 3 mL bacteriostatic water to a 10 mg vial.
Timing
On an empty stomach, 30 minutes before meals.
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Potential Side Effects
- Increased appetite (significant)
- Water retention
- Tingling or numbness in extremities
- Elevated cortisol at high doses
Important Warnings
- Can significantly elevate cortisol and prolactin at high doses
- Do not use with active cancer
- WADA-prohibited substance
Works Well With
Research References
- Bowers CY. J Clin Endocrinol Metab. 2001;86(4):1464-1469. doi:10.1210/jcem.86.4.7399
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Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. GHRP-2 may be regulated differently in various jurisdictions. Always consult with a qualified healthcare provider before beginning any peptide protocol. PepStack Pro does not sell peptides or provide medical advice. Content reviewed by Dr. Seth Miller, MD.