CJC-1295 with DAC
CJC-1295 with Drug Affinity Complex (DAC) is a modified growth hormone releasing hormone analog that binds to albumin in the bloodstream, dramatically extending its half-life to 6-8 days. This means a single injection provides sustained, elevated GH levels for nearly a week — unlike the pulsatile release of CJC-1295 without DAC. The constant GH elevation mimics a more youthful GH profile. However, because it does not produce sharp GH pulses, some prefer the no-DAC version for more natural signaling.
Frequency
1-2x per week
Cycle Length
8-12 weeks on, 4-6 weeks off
Route
Subcutaneous
Research Level
Emerging
Goals
Dosing Protocol
2-4 mg per dose, 1-2 times per week. No more than 4 mg per week. With standard reconstitution (10 mg in 1 mL), 0.1 mg per unit — 20 units = 2 mg, 40 units = 4 mg on a U-100 insulin syringe.
Reconstitution
Add 1 mL bacteriostatic water to a 10 mg vial.
Timing
Can be injected at any time due to long half-life. Many prefer before bed.
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Potential Side Effects
- Water retention
- Tingling in extremities
- Fatigue initially
- Potential cortisol blunting with prolonged use
Important Warnings
- Do not use with active cancer — sustained GH elevation may promote tumor growth
- Monitor IGF-1 levels regularly
- WADA-prohibited substance
Frequently Asked Questions
What does CJC-1295 with DAC do?
CJC-1295 with DAC is a long-acting growth-hormone-releasing hormone analog. Its main appeal is sustained elevation of growth hormone and IGF-1 over several days rather than short pulses.
How often is CJC-1295 with DAC usually taken?
CJC-1295 with DAC is usually taken 1 to 2 times per week because the DAC modification extends the half-life significantly compared with shorter-acting GH secretagogues.
What is the difference between CJC-1295 with DAC and no DAC?
The DAC version is longer acting and produces a more sustained signal. No-DAC versions are typically used when people want shorter, more pulsatile growth hormone release.
Can CJC-1295 be stacked with Ipamorelin?
Yes. CJC-1295 and Ipamorelin are one of the best-known GH-support stacks, although the exact version of CJC-1295 and the dosing strategy should match the goal and monitoring plan.
Research References
- Teichman SL, et al. J Clin Endocrinol Metab. 2006;91(3):799-805. doi:10.1210/jc.2005-0803
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Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. CJC-1295 with DAC may be regulated differently in various jurisdictions. Always consult with a qualified healthcare provider before beginning any peptide protocol. PepStack Pro does not sell peptides or provide medical advice. Content reviewed by Dr. Seth Miller, MD.